07.30 - 08.30 Registration
09.00 - 09.00 Opening
keynote lecture
09.15 - 10.15 Kiyoshi Nagai. Structure
of the spliceosomal U1 snRNP
10.15 - 10.45 Coffee break
Regulation and Structure I
10.45 - 11.05 Joao
Tavanez. HnRNP A1 confers specificity to 3' splice site recognition by U2AF
11.05 - 11.25 Vladimir
Pena. Structure reveals functions at the core of the spliceosome
11.25 - 11.45 Mireya Plass. Role of RNA secondary structure in 3'ss
regulation in yeast
11.45 - 12.30 Michael
Sattler. Structural biology and dynamics in the regulation of pre-mRNA splicing
12.30 - 13.40 Lunch
break
Regulation and Structure II
13.40 - 14.00 Quaid Morris. RNAcompete: a fast and inexpensive method for
comprehensively assaying the binding preferences of RNA-binding proteins
14.00 - 14.20 Markus
Blatter. NMR structure of hnRNP L in complex with RNA
14.20 - 14.40 Monika
Heiner. The heterogeneous ribonucleoprotein L-like,
a master regulator of alternative splicing in immune cell development?
14.40 - 15.25 Gabriele
Varani. Recognition of transcription termination
signals by RNA processing factors
15.30 - 16.00 Coffee
break
Regulation and Networks I
16.00 -
16.20 Andreas
Dahlgren (Illumina). Illumina Genome Analyzer System
16.20 - 17.05 Ben
Blencowe. Alternative splicing regulatory networks
17.10 - 18.30 Poster
session
followed by Conference dinner
Program, June 28th
Regulation and Networks II
09.00 - 09.45 Barbara Wold. RNA-Seq analysis
of mammalian transcriptomes
and their relationship to regulatory networks
09.45 - 10.05 Rickard Sandberg. MRNA-sequence analyses of tissue transcriptomes reveals compositional
differences and isoform regulation
10.15 -
10.45 Coffee
break
Comparative Analyses
10.45 - 11.05 Chris Lee. Predicting
functional alternative splicing by measuring RNA selection pressure from 28
vertebrate genomes
11.05 - 11.25 Ernesto Picardi. A survey
of alternative splicing in Vitis vinifera and assesment by Illumina short
sequencing reads
11.25 - 11.45 Martin
Pohl. Computational analysis shows mutually exclusive exons are predominantly
not adjacent to each other and can be spliced as clusters
11.45 - 12.30 Gene Yeo. Analysis of
RNA binding maps
12.30 - 14.00 Lunch break
Specific Mechanisms of
Regulation
14.00 - 14.20 Andrew
Berglund. The mechanisms of MBNL1 regulated splicing and small molecule that
reverses the splicing defects associated with myotonic dystrophy
14.20 - 14.40 Minna-Liisa Anko. SRp75 and SRp20
regulate gene expression by binding to specific transcripts
14.40 – 15.00 Mikko Frilander. Cellular U11 snRNP levels
regulates evolutionary conserved alternative splicing of U11/U12-48K and -65K
genes
Genome Wide Analyses
15.00 – 15.20 Gary P. Schroth (Illumina). Improved RNA Analysis Methods for the Illumina
Genome Analyzer
15.30 - 16.00 Coffee
break
16.00- 16.20 Asim Siddiqui. (Applied
Biosystems). Detecting known and novel splicing events in the human transcriptome by
high throughput sequencing
16.20 - 16.45 Mohsen Khorshid. Transcriptome-wide
miRNA-target site identification by direct sequencing
of Argonaute-bound mRNA segments
16.45
- 17.05 Hagen Tilgner. Nucleosome
Positioning is a determinant of Exon recognition
17.05
- 17.25 Michael
Tress. Confirming Alternative protein isoforms in
Drosophila
17.25 - 18.10 Jernej Ule. The evolution
of functional interactions between TDP-43 and pre-mRNAs
18.15 Conclusion